Aichun Dong

Faculty

Professor

Email aichun.dong@unco.edu
Phone (970) 351-1284
Location Ross Hall, Office 2576
Address 501 20th St., Campus Box 98, Greeley, CO 80639

Education

Post Doc, University of Colorado Health Science Center, 1995.
Area of Study: Pharmaceutical Sciences

Post Doc, Colorado State University, 1994.
Area of Study: Biochemistry

PhD, Colorado State University, 1990.
Area of Study: Biochemistry

MD, Guangxi Medical University, 1972.
Area of Study: Medicine

Research Expertise & Interests

Areas of Interest

My research focuses on understanding and elucidating the structural changes in proteins using infrared spectroscopy.

Chemical and Thermal Induced Conformational Changes of alpha-Crystallin Adsorbed on Aluminum Hydroxide by FT-IR Spectroscopy
Effects of mutation on the thermal stability of cystathionine beta-synthase as determined by FT-IR spectroscopy
FTIR spectroscopic analysis of all 20 Amino acids in physiologically relevant solutions

Publications

  • Yang, H.Y., Yang, S.-N., Kong, J.-L., Dong, A., & Yu, S.-N. “Obtaining information about protein structures in aqueous solution using Fourier transform IR spectroscopy.” Nature Protocols 10, 381-396, 2015.
  • Wu, G.-R., Gao, Z.-Y., Dong, A. and Yu, S.-N.”Calcium-induced changes in calmodulin structural dynamics and thermodynamics.” Intl. J. Biol. Macromol. 50, 1011-1017, 2012.
  • Hoehne, M. Samuel, F.; Dong, A., Wurth, C.; Mahler, H.-C; Carpenter, J.F. and Randolph, T. “Adsorption of Monoclonal Antibodies to Glass Microparticles.” J. Pharm. Sci. 100. 123-132,2010.
  • Bai, S.-F., and Dong A. “Effects of immobilization onto aluminum hydroxide particles on the thermally induced conformational behavior of three model proteins.” Intl. J. Biol. Macromol. 45, 80-85, 2009.
  • Dutka, M.D., Dong, A., and Schwenz, R.W. “A Raman experiment exploring the definition of a strong acid. ” Chem. Educator, 14, 16-18, 2009.
  • Tyagi, A.K., Randolph, T.W., Dong, A., Maloney, K.M., Hitscherich Jr., C., and Carpenter, J.F. “IgG particle formation during filling pump operation: A case study of heterogeneous nucleation on stainless steel nanoparticles.” J. Pharm. Sci. 98, 94-109, 2009.
  • Shen, X.-R., Li, H.-M., Ou, Y., Tao, W.-B., Dong, A., Kong, J.-L., Ji, C.-N., and Yu, S.-N. “The secondary structure of calcineurin regulatory region and conformational change induced by calcium/calmodulin binding.” J. Biol. Chem. 283, 11407-11413, 2008.