Kui Chen

Contact Information

Education

Post doctoral fellow (bionanophotonics) – Oak Ridge National Laboratory, Oak Ridge, TN
Ph.D. (Analytical Chemistry) – University of South Carolina, Columbia, SC
B.S. (Chemistry) – Xiamen University, Xiamen, Fujian (China)

Research/Areas of Interest

My research interest is in the area of nanobiophotonics which integrates advances in nanotechnology and different optical spectroscopic techniques for biomedical and bioanalytical applications. A common theme of my research is to explore the surface plasmonic properties of metallic nanoparticles for designing innovative sensing, imaging and therapeutic agents. Surface-enhanced Raman scattering (SERS) and fluorescence will be the primary optical spectroscopic techniques that will be employed. Potential projects involves synthesis, characterization and surface modification of metallic nanoparticles as a photothermal therapeutic agent and as SERS substrate.

Publications/Creative Works

Recent Publications

• K. Chen, I. Soto, W. T. Monroe, J. S. Alexander, “Photothermolysis of lymphatic endothelial cells by gold nanoshell-mediated hyperthermia”, Journal of Nanoscience and Nanotechnology, 2014, 14(7), 5347.
• G. Grant, J. Li, Y. Zhang, S. Li, C. Wilson, K. Chen, T. Vo-Dinh, Q. Liu, "Compact point-detection fluorescence spectroscopy system for quantifying intrinsic fluorescence redox ratio in brain cancer diagnostics", Journal of Biomedical Optics, 2011, 16(3), 037004.
• K. Chen, T. Vo-Dinh, "Single Molecule Detection and Activity Monitoring at the Nanoscale Level in Fixed and Living Cells by Optical Spectroscopy", Book Chapter, in: Nanotechnology in Biology and Medicine - Methods, Devices, and Applications, Vo-Dinh T. (ed.), CRC Press, Boca Raton, FL. 16-1 (2007).
• K. Chen, M. Leona,T. Vo-Dinh, "Surface-Enhanced Raman Scattering for Identification of Organic Pigments and Dyes in Works of Art and Cultural Heritage Material", Sensor Review, 2007, 27, 109.
• Q. Liu, K. Chen, M. E. Martin, A. Wintenberg, R. Lenarduzzi, M. Panjehpour, B. F. Overholt, and T. Vo-Dinh "Development of a synchronous fluorescence imaging system and data analysis methods", Optics Express, 2007, 15, 12583.
• K. Chen, M. Leona,K-C. Vo-Dinh, F. Yan, M. B. Wabuyele, T. Vo-Dinh, "Application of surface-enhanced Raman scattering (SERS) for the identification of anthraquinone dyes used in works of art", Journal of Raman Spectroscopy, 2006, 37, 520.
• M. E. Martin, M. B. Wabuyele, K. Chen, P. M. Kasili, M. Panjehpour, M. Phan, B. Overholt, G. Cunningham, D. Wilson, R. C. DeNovo, and T. Vo-Dinh, "Development of an Advanced Hyperspectral Imaging (HSI)System with Applications for Cancer Detection", Annals of Biomedical Engineering, 2006, 34, 106.