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Reid Hayward, Ph.D.

Reid Hayward, Ph.D.

Professor, Sport and Exercise Science

School of Sport and Exercise Science
College of Natural and Health Sciences

Contact Information

2780 Gunter Hall
Mailing Address
University of Northern Colorado
School of Sport and Exercise Science
Campus Box 39
Greeley, CO 80639


1996 – PhD, University of Arkansas, Fayetteville, AR

1993 – MS, University of Kansas, Lawrence, KS

1991 – BS, Harding University, Searcy, AR

Professional/Academic Experience

1996 – 1998:     Postdoctoral Research Fellow, Thomas Jefferson University , Jefferson Medical College , Philadelphia , PA

1998 – 2004:     Assistant Professor of Sport and Exercise Science, University of Northern Colorado , Greeley , CO

2004 – 2009:     Associate Professor of Sport and Exercise Science, University of Northern Colorado, Greeley, CO

2009 –                Professor of Sport and Exercise Science, University of Northern Colorado, Greeley, CO

2013 –                Present; Director, University of Northern Colorado Cancer Rehabilitation Institute, University of Northern Colorado, Greeley, CO

Research/Areas of Interest

Dr. Hayward is a Professor of Sport and Exercise Science and the Director of the University of Northern Colorado Cancer Rehabilitation Institute (www.unco.edu/unccri). The focus of our work is to improve the quality of life for cancer survivors by providing clinical exercise-based rehabilitation programs, by educating those individuals who provide exercise-based rehabilitation services, and by conducting basic and applied research that advances our understanding of cancer rehabilitation. As the Director of UNCCRI, Dr. Hayward oversees all clinical, educational, and research activities of the Institute.

Patients enrolled in our cancer rehabilitation program serve as subjects in a wide array of research studies conducted by students in our undergraduate and graduate programs at the University of Northern Colorado. Clinical research conducted at UNCCRI utilizes a multidisciplinary approach which focuses primarily on: 1) the physiological adaptations that occur in cancer survivors during exercise training, 2) identifying the exercise intensity, duration, and modality that provides the greatest benefit for cancer survivors, 3) optimizing current techniques involved with exercise assessment and prescription in cancer survivors, and 4) understanding the effects of exercise on biomarkers of prognosis and survival in cancer survivors.

In order to further understand mechanisms that may explain the beneficial effects of exercise in cancer survivors, we utilize tumor-bearing rodent models to study the effects of exercise on various physiological systems with a particular interest in cardiovascular function. We evaluate in vivo cardiac function in rodent models using a General Electric Vivid 7 ultrasound with intraoperative probes capable of evaluating cardiac function in both rats and mice. Ex vivo cardiac function is evaluated using an isolated perfused rodent heart apparatus that allows for the quantification of cardiac pressures, volumes, and flow under controlled conditions. We also utilize cell culture techniques to maintain multiple tumor cell lines (metastatic and nonmetastatic) that are used in rat and mouse tumor-bearing models. Our facilities are equipped with modern wet laboratory equipment necessary to conduct an array of biological experiments including protein analyses and spectrophotometry. Our research focuses primarily on: 1) understanding mechanisms by which exercise attenuates chemotherapy-induced cardiotoxicity associated with standard cancer treatments such as anthracyclines, 2) the deleterious effects of cancer on cardiac function and how exercise can mitigate cancer/cachexia-induced cardiac dysfunction, and 3) the interaction of cancer, chemotherapy, and exercise on clinical biomarkers of cancer prognosis and survival.

Publications/Creative Works

  1. Parry TL, Hayward R. Exercise Protects Against Cancer-Induced Cardiac Cachexia. Medicine and Science in Sports and Exercise (in press).
  2. Repka CP, Hayward R.  Effects of an Exercise Intervention on Cancer-Related Fatigue and its Relationship to Markers of Oxidative Stress. Integrative Cancer Therapies (inpress).
  3. Peterson BM, Brown JM, Shackelford DYK, Olson T, Lalonde TL, Hayward R.  Implications of Physical Activity History on Initial Physiological and Psychosocial Variables in Cancer Survivors Entering a Cancer Rehabilitation Program. Journal of Clinical Exercise Physiology (inpress).
  4. Pfannenstiel K, Hayward R. Effects of Resistance Exercise Training on Doxorubicin-Induced Cardiotoxicity.  Journal of Cardiovascular Pharmacology (inpress).
  5. Peterson BM, Johnson C, Case K, Shackelford DYK, Brown JM, Lalonde TL, Hayward R. Cancer Rehabilitation: Impact of Physical Activity on Initial Clinical Assessments. Pilot and Feasibility Studies4:50-61, 2018.
  6. Dunne RF, Mustian KM, Garcia JM, Dale W, Hayward R, Roussel B, Buschmann MM, Caan BJ, Cole C, Fleming FJ, Chakkalakal JV, Linehan DC, Hezel AF, Mohile S G.  Research priorities in cancer cachexia: The University of Rochester Cancer Center NCI Community Oncology Research Program Research Base Symposium on Cancer Cachexia and Sarcopenia. Current Opinion in Supportive and Palliative Care 11:278-286, 2017.
  7. Shackelford DYK, Brown JM, Peterson BM, Schaffer J, Hayward R. Validation of the University of Northern Colorado Cancer Rehabilitation Institute Treadmill Protocol. International Journal of Physical Medicine and Rehabilitation 5:437, 2017. [Link]
  8. Vin-Raviv N, Akinyemiju T, Qingrui M, Sakuja S, Hayward R. Marijuana Use and Inpatient Outcomes among Hospitalized Patients: Analysis of the Nationwide Inpatient Sample Database. Cancer Medicine 6:320-329, 2017.
  9. O’Brien K, Boeneke C, Prinyawiwatkul W, Lisano J, Shackelford D, Reeves K, Christensen M, Hayward R, Carabante KC, Ordonez, Stewart LK. Sensory Analysis of a Kefir Product Designed for Active Cancer Survivors. Journal of Dairy Science 100:4349–4353, 2017.
  10. Repka CP, Hayward R.  Oxidative Stress and Fitness Changes in Cancer Patients Following Exercise Training. Medicine and Science in Sport and Exercise 48:607-614, 2016.
  11. Bredahl EC, Pfannenstiel KB, Quinn CJ, Hayward R, Hydock DS. Effects of Exercise on Doxorubicin-Induced Skeletal Muscle Dysfunction. Medicine and Science in Sport and Exercise 48:1468–1473, 2016.
  12. Quinn CJ, Burns PD, Gibson NM, Bashore A, Hayward R, Hydock DS. Effects of Chronic Exercise on Doxorubicin-Induced Thymic Damage. Integrative Cancer Therapies 15:535-541, 2016.
  13. Quinn CJ, Gibson NM, Pfannenstiel KB, Bashore AC, Hayward R, Hydock DS. Effects of exercise on doxorubicin accumulation and multidrug resistance protein expression in striated muscle. Global Journal of Medical Research 16: 11-22, 2016.
  14. Parry TL, Hayward R. Exercise Training Does Not Affect Anthracycline Anti-Tumor Efficacy While Attenuating Cardiac Dysfunction. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology309: R675-R683, 2015. 
  15. Lien C-Y, Jensen BT, Hydock DS, Hayward R. Short-Term Exercise Training Attenuates Acute Doxorubicin Cardiotoxicity. Journal of Physiology and Biochemistry 71: 669-678, 2015.

Complete list at http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/49601234/?sort=date&direction=descending