Michael Mosher

Email: michael.mosher@unco.edu

Phone: 351-1443

Professor of Organic Chemistry and chair of the Department of Chemistry and Biochemistry. Specialist in the design and preparation of molecules that contain nitrogen and oxygen. His research involves the development of new methods for the preparation of those molecules and the study of their interactions with biological systems. In particular, his research focuses on the design and study of anti-Type 1 diabetes and anti-cancer drugs.

Websites:

Topics:

Drug - DNA Interactions

Design, synthesis, and interaction of acridine-based drugs with DNA.

Heterocyclic Organic Synthesis

Development of new routes to the preparation of nitrogen and oxygen containing molecules. Study of those reactions and identification of procedures that are less hazardous than currently used.

Preparation of Type 1 Diabetes drugs

Design, synthesis, and evaluation of compounds that interact with macrophage migration inhibitory factor (MIF). Development of new procedures to the preparation of existing antagonists of MIF. Application of antagonism to other diseases based on this inflammatory response.