Institutional Review Board (IRB) for the Protection of Human Subjects in Research

POSSIBLE UPDATES: IRB FEDERAL REGULATIONS – EFFECTIVE JANUARY 19, 2018

IRBNet

All research projects conducted under the auspices of the university (e.g. by faculty, students, or staff) involving human subjects must be reviewed and approved by the university's Institutional Review Board (IRB). Faculty, students and staff planning human research must submit requests for IRB approval prior to any data collection.

UNC Regulations and procedures regarding the use of human subjects are guided by the ethical principles set forth in the Belmont Report. The university and the IRB adhere to the federal regulations found at CFR Title 45, Part 46. The role of the IRB is to support UNC researchers in conforming to the ethical standards for the protection of human subjects, researchers, and the university. The IRB is committed to carrying out this charge in a manner that will support and assist researchers.

The use of human subjects in research at UNC is regulated by University Regulations 3-8-104, enacted by the Board of Trustees to ensure that all research involving human subjects carried out under the auspices of UNC conforms to ethical standards.

3-8-104 Human Subjects. It is the policy of the University that all research and research-related activities, in which humans are used as subjects, shall be subject to review under current Public Health Service regulations by an Institutional Review Board (IRB). The involvement of humans subjects in research covered by this policy shall be prohibited until the IRB has reviewed and approved the research protocol.

Have Questions?

Visit our FAQ page.

IRB Guidance

UNC has implemented the IRBNet system to streamline the IRB application and review process. IRBNet provides a paperless, electronic method for submission, tracking and review of applications for IRB approval. Researchers can create, edit, and submit their applications for IRB approval, and IRB members can review and take action on applications at any time from any computer with Internet access.

Additional Resources