Carole M. Schneider, Ph.D.Education
Professional Experience
ResearchThe primary focus of our laboratory is the use of pharmacological and non-pharmacological (physical activity) interventions to attenuate the deleterious cardiovascular side effects of chemotherapy in human and animal models. We use human cancer survivors to determine the effects of exercise on cancer treatment related toxicities and symptoms. We use animal models of chemotherapy-induced organ toxicity to examine the benefits of specific drugs and exercise in alleviating the deleterious side effects of cancer treatments. Our laboratory uses modern physiological, biochemical, and histological techniques to assess the degree of protection provided by treatment interventions. Selected PublicationsSchneider, C.S., Hsieh, C.C., Sprod, L.K., Carter, S.D. and Hayward, R. Cancer Treatment-induced Alterations in Muscular Fitness and Quality of Life: the Role of Exercise Training. Annals of Oncology (in press). Schneider, C.S., Hsieh, C.C., Sprod, L.K., Carter, S.D. and Hayward, R. Effects of Supervised Exercise Training on Cardiopulmonary Function and Fatigue in Breast Cancer Survivors During and After Treatment. Cancer 110:918-925, 2007. (Summary on BreastCancer.Net News) Schneider, C.S., Hsieh, C.C., Sprod, L.K., Carter, S.D. and Hayward, R. Exercise Training Manages Cardiopulmonary Function and Fatigue During and Following Cancer Treatment in Male Cancer Survivors. Integrative Cancer Therapies 6(3):235-241, 2007. Hydock, D.S., Wonders, K.Y., Schneider, C.M. and Hayward, R. Androgen Deprivation Therapy and Cardiac Function: Effects of endurance training. Prostate Cancer and Prostatic Disease 9:392-398, 2006. Chicco A, Schneider CM, Hayward R. Low intensity exercise training protects against doxorubicin cardiotoxicity. Journal Applied Physiology 100: 519-527, 2006. Chicco A, Hydock DS, Schneider CM, Hayward R. Exercise training attenuates acute doxorubicin-induced cardiac dysfunction. Journal of Cardiovascular Pharmacology 47: 181-188, 2006. Chicco A, Schneider CM, Hayward R. Voluntary exercise protects against doxorubicin cardiotoxicity in the isolated perfused rat heart. American Journal of Physiology: Regulatory, Integrative, and Comparative Physiology 289: R424-R431, 2005. Hayward R , Ruangthai R, Schneider CM, McCarty H, Hyslop R, Strange R, Westerlind K. Training Enhances Vascular Relaxation Following Chemotherapy-Induced Vasoconstriction. Medicine and Science in Sports and Exercise 36: 428-434, 2004. Schneider, C.M, C.A. Dennehy, and S.D. Carter. Exercise and Cancer Recovery. 1st edition, Illinois: Human Kinetics, 2003. Carter SD, Drum SN, Hayward R, Schneider CM. A Case Study: Prescriptive Exercise Intervention After Bilateral Mastectomies. Integrative Cancer Therapies 2: 34-38, 2003. Schneider, C.M., C.A. Dennehy, M. Roozeboom, & S.D. Carter. A Model Program: Exercise Invervention for Cancer Rehabilitation. Intergrative Cancer Therapies, 1(1):76-82, 2002. Hayward R, Ferrington DA, Kochanowski LA, Miller LM, Jaworsky GM, Schneider CM. Effects of dietary protein on serum and muscle enzyme activity following exercise-induced muscle injury. Medicine and Science in Sports and Exercise 31: 414-420, 1999. |
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